Certified Rehabilitation Counselor Practice

Which brain chemical is linked to depression when imbalanced?

1. Acetylcholine

2. Dopamine

3. GABA

4. Adrenaline

The correct answer is: Dopamine

Dopamine is a critical neurotransmitter that plays a significant role in regulating mood, motivation, and pleasure. An imbalance or deficiency of dopamine in the brain has been strongly associated with various mental health conditions, particularly depression. This neurotransmitter is integral to the brain's reward system; when its levels are low, individuals may experience feelings of apathy, low energy, and an inability to feel pleasure—typical symptoms of depression. While other neurotransmitters like serotonin and norepinephrine also play roles in depression, dopamine stands out because its link to motivation and reward directly impacts how a person experiences pleasure in life. This connection to reward and motivation makes its proper balance essential for emotional well-being. Acetylcholine, GABA, and adrenaline, while important in various brain functions and related to other mental health concerns, do not have the same direct link to the experience of depression when imbalanced as dopamine does. Therefore, dopamine is the most pertinent choice in regard to its established relationship with depression.